Pinky and the Brain is an American animated television series. It was the first animated television series to be presented in Dolby Surround and the fourth collaboration of Steven Spielberg with his production company, Amblin Entertainment, and produced by Warner Bros. Animation. The characters first appeared in 1993 as a recurring segment on Animaniacs and then from 1995 to 1998, they were spun off into their own show on Kids' WB, Steven Spielberg Presents Pinky and the Brain, with 65 episodes produced. Later, they appeared in the award-winning series, Steven Spielberg Presents Pinky, Elmyra and the Brain.
Pinky and Brain are genetically enhanced laboratory mice who reside in a cage in the Acme Labs research facility. Brain is self-centered and scheming; Pinky is good-natured but feebleminded. In each episode, Brain devises a new plan to take over the worldwhich ultimately ends in failure: usually due to Pinky's idiocy, the impossibility of Brain's plan, Brain's own arrogance, or just circumstances beyond their control. In common with many other Animaniacs shorts, many episodes are in some way a parody of something else, usually a film or novel. The spin off of this show is Pinky, Elmyra and the Brain.